Scientific infographic on metabolic starvation showing selective drug action on fungal DHODH, with no impact on human cells.

A clean, professional scientific infographic diagram on a plain white background with the bold title at the top center: "Metabolic Starvation: The Pyrimidine Factory". Below the title, the diagram is divided into two main side-by-side panels within a simplified background flow chart representing the "Pyrimidine Salvage Pathway". At the very top background, faint arrows show "Precursors" leading to an intermediate labeled "Dihydroorotate", which feeds into the central action of the two panels. Left Panel: "Fungal DHODH (Target)" The left panel is headed with the bold title "FUNGAL DHODH (Target)". Below it, a large, complex, stylized enzyme protein structure rendered in green tones is labeled "Fungal DHODH". It possesses a specifically shaped binding pocket. A distinct, small, geometric drug molecule, colored bright red and labeled "F901318 (Olorofim)", is shown snugly and tightly locked into this binding pocket, perfectly fitting like a piece in a puzzle. Radiating red lines around the binding site indicate a strong, tight interaction. A large, bold red "X" is overlaid on the entire green enzyme structure. A thick red inhibition "T-bar" symbol blocks the pathway arrow exiting the enzyme. Below this blocked enzyme, bold text reads: "RESULT: Factory Shutdown. Fungal Starvation." Central Selectivity Highlight Separating the left and right panels is a prominent central graphic element emphasizing the difference. A large arrow points between the two panels with a central text box See more