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Scientific diagram showing IRX4 gene's role in prostate cancer with graphs and molecular structures.

Scientific diagram showing IRX4 gene's role in prostate cancer with graphs and molecular structures.

first draw prostate cancer risk snp affect and IRX4 gene transcritipton. then show this irx4 expression goes high from normal prostate into primary prostate cancer, castration sentive metastatic cancer and reduce in castration resistant prostate cancer. then draw in castration sensitive prostate cancer IRX4 physically interactsts with FOXA1 and then ultimately AR and affect AR signalling and then show IRX4 promoter region has a AR binding peaks in some patients and not in others. Those who dont have AR binding peaks in IRX4 gene they die sooner and resistant t androgen deprivation therapy. ADD 3D IMAGES See more